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How Tadalafil Works

Before we explain how Tadalafil helps manage ED, we need to explain how erections occur naturally. When you become aroused, your body releases a substance called nitric oxide (NO). In turn, levels of a chemical known as cyclic guanosine monophosphate (cGMP) increase in your body, relaxing the muscles on the sides of your penis so blood can flow into the organ and trigger a stiff erection.

While all this is happening, your body also compresses the veins that take blood away from the penis, so that the blood remains in place and you can maintain that erection. Eventually, the PDE5 enzyme in your body gets to work, and it processes the cGMP. When that happens, your erection dissipates, and the penis becomes flaccid once again.

If you have ED, regardless of the underlying cause, this natural process is somehow interrupted. That makes it more difficult for you to get or maintain an erection that’s sufficient for intercourse. And that’s where Tadalafil, a PDE5 inhibitor, can help. By blocking this enzyme in your body, you’ll have an easier time getting an erection and holding on to it until sex is complete.

As we mentioned earlier, ED can be caused by various factors, including psychological factors, psychiatricumers, pregnancy, childbirth, and other factors that may interact with tadalafil. When you become aroused, your body releases nitric oxide (NO), which builds up in your body, causing your body to release tadalafil.

If you have a weakened or compounding medical condition, you may be more likely to be experiencing ED. When you become sexually aroused, you’ll increase the amount of tadalafil in your system by taking a pill or supplement. And while taking a tadalafil supplement can be helpful, it’s important to note that that medication should only be taken under the guidance of a healthcare professional. If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Don’t take a double dose to make up for a missed dose.

How Tadalafil Works for You

As mentioned earlier, ED can be caused by various factors, including psychological factors, psychiatricumers, pregnancy, and other factors that may interact with tadalafil. However, if it’s almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Don’t take a tadalafil dosage to make up for a missed dose..

Tadalafil for Daily Use

As we mentioned earlier, ED can be caused by psychological factors, psychiatricumers, pregnancy, and other factors that may interact with tadalafil. When you become sexually aroused, you’ll increase the amount of tadalafil in your system by taking a pill. And while taking a tadalafil dosage for daily use, avoid taking that double dose because it may increase the risk of experiencing side effects..

This makes it more difficult for you to get an erection that’s adequate for sex. And that’s not even getting by if you’re having sex with a partner who isn’t erection-producing.

As we mentioned earlier, ED can be caused by various factors, including psychological factors, psychiatricumers, pregnancy, and other factors that may interact with tadalafil.

Cialis Together for Erectile Dysfunction

Cialis Together tablets are a treatment for adult men who have erection problems (erectile dysfunction). This is when a man cannot get, or keep an erection hard enough for satisfactory sexual activity.

Cialis Together tablets contain the active substance tadalafil. It belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing the blood vessels in your penis, allowing blood flow into your penis.

It is important to know that you will not get an erection just by taking Cialis Together tablets. This medicine works with your body’s natural function to get an erection only when you are sexually stimulated.

Cialis Together contains the active ingredient Tadalafil. The ingredient is a phosphodiesterase type 5 inhibitor medicine that temporarily improves blood flow to the penis by relaxing the blood vessels in and around the area.

The Cialis Together medication is available over-the-counter and begins to work about 30 to 60 minutes after taking it. The effects are expected to last up to 36 hours. Cialis Together comes in 10mg tablets and should only be taken when needed.

The active substance Tadalafil is also useful in treating other conditions along with erectile dysfunction. Please consult a Doctor, a Pharmacist or relevant product literature for more information.

Is Cialis Together right for me?

If you suffer from erectile dysfunction (impotence) Cialis Together may be an effective treatment. However, it may not be suitable for you if you have the following:

  • If you are allergic to any of the ingredients in Cialis Together
  • If you have severe heart, liver or kidney problems
  • If you have blood pressure concerns
  • If you have non-arteritic anterior ischemic optic neuropathy
  • If you are taking riociguat
  • If you have other penis-related issues (deformation or painful erections)
Also, Cialis Together contains lower than always steroid doses and there is an an increased risk of side effects from an oral medication..

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Cialis Together is an easy to use Cialis Together tablet treatment. Just one one one one one one pill a day can cover the following:

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  • If you are taking any other medication please consult your doctor

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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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However, inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Cialis can also interact with nitrates used for chest pain, as this can cause a sudden and dangerous drop in blood pressure. As a result, you should avoid activities that can potentially lead to dizziness or fainting.

Tell them about any and all medications, prescription drugs, and supplements you are taking before starting Cialis. Cialis can cause an alpha-blocker such as tadalafil, which can potentially interact with other medications. As with all prescription medications, inform your doctor if you are currently taking any of the following medications:

  • Aspirin
  • Lidocaine
  • Medications for migraine
  • St. John’s wort
  • other antibiotics

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Here are the key drug-food interactions:

  1. : While grapefruit is usually the most common product, combining it with Cialis can enhance side effects like headaches or increase heart rate in sensitive individuals.
  2. : Though this combination may be more effective in sensitive individuals, simultaneous use of both medications is recommended while using Cialis.
  3. : While high-fat meals may delay the onset of Cialis's blood pressure-lowering effects, simultaneous use of both medications is recommended while using Cialis.
  4. : Though not a direct interaction, combining Cialis with highaffeine might worsen side effects in sensitive individuals.